64 live listingsUpdated

Used Mercedes W221 S-Class for sale

64 Mercedes W221 S-Class listings are live in our latest scan, from $8,400 up to $38,968. The median asking price is $18,255. Model years range from 2007 to 2013, the typical car shows 89,043 mi, and half are priced between $14,408 and $22,959.

The lowest-priced one is a 2009 Mercedes-Benz S-Class S 63 AMG listed at $8,400 with 163,500 mi in Miami, FL.

Our latest scan covers 3 versions of the Mercedes W221 S-Class: the S 63 AMG, S 600, and S 65 AMG. Like for like, the median Mercedes W221 S-Class S 600 asks $18,380, against $40,720 for the Mercedes W222 S-Class S 600 and $23,500 for the Mercedes W220 S-Class S 600.

Latest Mercedes W221 S-Class listings

All used S-Class

Mercedes W221 S-Class prices by model year

Median asking price of the Mercedes W221 S-Classes for sale in each model year, with how many are listed and their price range.

S-Class price guide
  1. 2013 $18,084 3 for sale · $14,149 to $19,311 · median 116,753 mi
  2. 2012 Mercedes-Benz S-Class for sale $26,493 8 for sale · $13,900 to $38,968 · median 78,959 mi
  3. 2011 Mercedes-Benz S-Class for sale $18,130 5 for sale · $14,494 to $28,999 · median 95,355 mi
  4. 2010 Mercedes-Benz S-Class for sale $13,895 6 for sale · $11,995 to $20,584 · median 130,366 mi
  5. 2009 Mercedes-Benz S-Class for sale $18,146 14 for sale · $8,400 to $34,999 · median 86,336 mi
  6. 2008 Mercedes-Benz S-Class for sale $18,380 21 for sale · $9,590 to $31,065 · median 85,507 mi
  7. 2007 Mercedes-Benz S-Class for sale $19,740 7 for sale · $12,995 to $30,298 · median 80,553 mi

Mercedes W221 S-Class versions for sale

Each version has its own page with deal analysis, market history and every deal we have found.

Version For sale Median price Lowest price
S 63 AMG 50 $18,107 $8,400
S 600 13 $18,380 $12,995
S 65 AMG 1 $30,298 $30,298

Mercedes W221 S-Class prices by mileage

Mileage For sale Median price Lowest price
15,000 to 30,000 miles 1 $34,999 $34,999
30,000 to 60,000 miles 7 $30,298 $21,500
Over 60,000 miles 56 $17,684 $8,400

Where used Mercedes W221 S-Classes are for sale

State For sale Median price Lowest price
California 12 $19,431 $14,950
Florida 7 $17,392 $8,400
Texas 6 $21,263 $12,800
Illinois 5 $15,344 $12,650
North Carolina 5 $14,900 $9,590
Georgia 4 $18,518 $15,789
New Jersey 3 $14,494 $12,788
New York 3 $22,724 $13,820
Virginia 3 $19,894 $11,995
Louisiana 2 $24,990 $24,990

Used Mercedes W221 S-Class: common questions

How much does a used Mercedes W221 S-Class cost?

Used Mercedes W221 S-Class asking prices currently range from $8,400 to $38,968, with a median of $18,255 across 64 listings. Half of them are priced between $14,408 and $22,959.

What is the cheapest Mercedes W221 S-Class for sale right now?

The lowest asking price in our latest scan is a 2009 Mercedes-Benz S-Class S 63 AMG listed at $8,400 with 163,500 mi in Miami, FL.

Which Mercedes W221 S-Class model years are for sale?

Listings span 2007 to 2013. The 2008 model year has the most cars for sale (21, median $18,380). The newest 2013 cars have a median asking price of $18,084, versus $19,740 for 2007.

Where are the most Mercedes W221 S-Classes for sale?

California (12), Florida (7), and Texas (6) have the most listings. Among states with at least 5 listings, median asking prices are lowest in North Carolina ($14,900) and highest in Texas ($21,263).

How many miles do used Mercedes W221 S-Classes for sale have?

The median Mercedes W221 S-Class for sale shows 89,043 mi. 0 of 64 listings (0%) have under 15,000 miles.

How long do Mercedes W221 S-Classes stay on the market?

Current Mercedes W221 S-Class listings have been for sale for a median of 49 days. Cars that sit well beyond that are often the easiest to negotiate on.

How current is this data?

These numbers come from our latest scan of dealer listings on Nov 4, 2026. Luxury Car Deals rescans the market regularly and removes cars that have sold.

Which Mercedes W221 S-Class versions are for sale?

Our latest scan lists the S 63 AMG (50), the S 600 (13), and the S 65 AMG (1).

How do Mercedes W221 S-Class prices compare with other generations?

Comparing the same trim, the median Mercedes W221 S-Class S 600 asks $18,380, against $40,720 for the Mercedes W222 S-Class S 600 and $23,500 for the Mercedes W220 S-Class S 600.